Objective: To optimize microwave-assisted extraction technology of Pingtang capsules B. Method: Pingtang capsules B was extracted by microwave assisted technology

with yield of geniposide as index

choosing microwave power

material-liquid ratio

extraction time

extraction times as investigating factors

orthogonal test was adopted to optimize microwave assisted extraction technology.The content of geniposide was determined by HPLC

chromatographic conditions were as follows:DiamonsilTM RP C18 column(4.6 mm×250 mm

5 μm)

mobile phase of acetonitrile-water(11: 89)

flow rate 1.0 mL·min-1

detection wavelength 238 nm

column temperature at room temperature

injection volume 20 μL. Result: Optimum extraction technology conditions were as follows:microwave power 15 kW

solid-liquid rate 1: 5

extraction time 20 min

extraction 2 times;Under these conditions

average yield of geniposide was 9.08 mg·g-1. Conclusion: Optimized microwave assisted extraction technology had advantages of high efficiency

energy saving and time saving with great application value for industrial production of Pingtang capsules B.