CHEN Mian, ZHANG Yan. Clinical Effect of Traditional Chinese and Western Medicine for Acute Coronary Syndrome and Influence for Serum hs-CRP and IL-6[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(22): 317-320.
CHEN Mian, ZHANG Yan. Clinical Effect of Traditional Chinese and Western Medicine for Acute Coronary Syndrome and Influence for Serum hs-CRP and IL-6[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(22): 317-320. DOI: 10.11653/syfj2013220317.
Objective: To explore the clinical effect of traditional Chinese and western medicine for acute coronary syndrome and the influence for serum high-sensitivity C-reactive protein(hs-CRP) and interleukin-6(IL-6).Method: One hundred and eighteen cases with acute coronary syndrome were randomly divided into control group and experience group. Control group were given routine western medicine and experience group were administrated with traditional Chinese and western medicine. 40 g Huangqi injection and 20 mL Danshen injection were dissolved into 250 mL sodium chloride injection respectively
quiescent point
once a day. The course of treatment was 2 weeks.Result: After treatment
the effective rates was much higher than that in control group (91.7% vs 75.9%
P<0.05);the dose of nitroglycerin in experience group was (1.47±0.52) tablets/week
of which was much less than that in control group[(3.40±0.87) tablets/week
P<0.05)]. After treatment
tcm syndrome evaluation in two groups were both decreased
while the tcm syndrome evaluation in experience group was superior to control group[(0.90±0.26) vs (1.33±0.41)paper
P<0.05]. The serum triglyceride(TC)
total cholesterol(TG)
hs-CRP and IL-6 after therapy in experience group were (4.89±0.96)
(1.60±0.52) mmol·L-1
(5.76±0.97) mg·L-1 and (76.59±14.38) ng·L-1
and of the above indexes in control group were (5.90±1.13)
(1.84±0.67) mmol·L-1
(7.36±1.03) mg·L-1 and (102.85±19.88) ng·L-1 with significant difference between two groups(P<0.05).Conclusion: Traditional Chinese and western medicine for acute coronary syndrome greatly decrease the serum inflammatory factor and blood lipid