Objective: To explore the effect of traditional chinese combined with western medicine in treatment of acne and the influence for negative emotion and life quality. Method: One hundred and twenty eight cases with acne were randomly divided into control group and experience group. Control group received routine western medicine therapy and experience group were given traditional chinese combined with western medicine treatment. Pepression self rating scale(SDS)

self assessment scales(SAS) scores and dermatology life quality index(DLQI) scale were used to evaluate negative emotion and life quality. Clinical effect and the change of negative emotion were compared between two groups. Result: The effective rates in experience group was much higher than that in control group (75.8% vs 56.5%

P<0.05);after treatment

SDS and SAS scores in experience group were (34.09±2.21)and (38.13±5.19)

of which were much lower than those in control group (38.17±2.64 and 46.80±5.76

P<0.05). The symptoms and feeling

daily activity

leisure entertainment

work and study

interpersonal relationship

therapy and total score of DLQI were(0.98±0.34)

(0.63±0.37)

(1.01±0.36)

(0.62±0.39)

(0.85±0.31)

(0.78±0.31)

(7.21±1.38) in experience group

and (0.98±0.34)

(0.63±0.37)

(1.01±0.36)

(0.62±0.39)

(0.85±0.31)

(0.78±0.31)

(7.21±1.38)in control group (P<0.05). Conclusion: Traditional chinese combined with western medicine for acne greatly improve the clinical effect

negative emotion and life quality.