BAI Ming, LIU Dan-dan, WANG Can, et al. Effects of Naomai Shukang Capsule on Mice Acute Cerebral Ischemia Model[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(24): 255-257.
BAI Ming, LIU Dan-dan, WANG Can, et al. Effects of Naomai Shukang Capsule on Mice Acute Cerebral Ischemia Model[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(24): 255-257. DOI: 10.11653/syfj2013240255.
Objective: To investigate the effects of Naomai Shukang capsule(NMSKC)on mice acute cerebral ischemia model. Method: Kunming mice were divided into six groups:Naomia Shukang capsule groups(4.0
2.0
1.0 g·kg-1)
model control group
positive medicine control groups(Huatuo Zaizao pill 2.67 g·kg-1
Nimodipine 0.02 g·kg-1).The mice acute cerebral ischemia model was established by rapid head-breaking method
and recorded the respiratory frequency and duration
the brain tissue was collected foe measurement of the contents of lactic acid (LD)
lactic dehydrogenase (LDH)
malondiadehyde (MDA) and superoxide dismutase (SOD)activity. Result: Naomai Shukang capsule could significantly increase respiratory rate and prolong respiratory and reduce the contents of LA and MDA
and increase the activities of LDH and SOD in brain tissue. Conclusion: Naomai Shukang capsule has protective effects on acute cerebral ischemia injury in mice.