Objective: To observe the anti-fatigue effect of Panax ginseng on qi deficiency model mice. Method: Mice were randomly divided into five groups:three treatment groups(P. ginseng orally given for 14 days

2.5

5

10 g·kg-1·d-1)

model group and control group. Applying Qi deficiency model mice induced by dietary restriction

P. ginseng was established with the changes of body weight

blood lactic acid

blood urea nitrogen and weight-loaded swimming test with computer-aided automatic control system for measuring swimming in mice. Result: P. ginseng can increase body weight. The level of blood lactic acid and blood urea nitrogen descended. The sink time

the death time

immobility time

swimming time

first sink time

swimming distance and immobility time rate in 10 g·kg-1 group was significantly prolonged and swimming time rate was shortened as compared with model group. Conclusion: P. ginseng has anti-fatigue effect on Qi deficiency model mice. It can enhance endurance of mice by prolonging immobility time rate and shortening swimming time rate.