Objective: To study the intervening effects on functional dyspepsia plus depression treated with Jiawei Sinisan

and the gastric emptying

motilin and gastrin were studied to demonstrate mechanism. Method: Ninety-six functional dyspepsia patients were randomly distributed into two groups

the control group treated with domperidone and St. John's wort extract

therapy group treated with taking orally Jiawei Sinisan

both course of treatment were 30 days

gastric emptying

motilin and Gastrin were studied before and after intervention

then general effect was evaluated. Result: The total effective rate was 93.75% in the therapy group whereas 77.08% in the control group

differences were significant(P < 0.05).Compared with control group

the motilin

gastrin and gastric emptying were better in therapy group

differences were significant(P < 0.05). Compared with control group

hamilton depression scale score better in the therapy group

differences were significant(P < 0.05). Conclusion: The effect of Jiawei Sinisan is certain

it could relieve clinlcal symptom of functional dyspepsia.