Objective: To systematic review the basic research's about the effect of borneol on neurotransmitters. Method: We searched Pub Med (1996 to 2012)

VIP (1989 to 2012)

Wan Fang Database (1990 to 2012)

CNKI (1979 to 2012)

and collected basic research literature related to borneol's impacts on neurotransmitter. The publications were screened

assessed and extracted valid data based on predetermined criteria. Result: A total of 11 basic researches were identified

found that borneol have a certain influence on content of monoamine

amino acids

beta-endorphin in central nervous system and catecholamine peripheral

and the outcome was related to the dose

the modeling methods

drawn parts

drawn time. One study showed that the central acetylcholine content have no difference between the experimental group and the control. Conclusion: Because of the researches obtain different methods

models

administration

the results are not uniform

difficult to prove each other

and the methodology and research system needs to be further strengthened.