Objective: Based on traditional cataplasmsmatrix materials

to optimize a novel formulation of cataplasms matrix materials. Method: With initial adhesion

peeling strength

phosphorus and sensory evaluation as comprehensive evaluation index

orthogonal test was adopted to optimize cataplasmsmatrix formulation by taking sodium polyacrylate

gelatin and sodium hyaluronate as adhesives

glycerol

propylene glycol and polyethylene glycol as moisturizers

attapulgite clay and zinc oxide as fillers

aluminum chloride as crosslinking agent. Result: Optimum matrix formulation was sodium polyacrylate-gelatin-sodium hyaluronate-glycerol-propylene glycol-polyethyleneglycol-AlCl3(4.5:2.5:2.0:13:13:13:0.2). Conclusion: These prepared cataplasmshad a certain application value with good initial adhesion

peeling strength

phosphorus and sensory.