Objective: To establish quality control method of Yao medicine Ardisia crispa

and provide the experimental basis for the formulation of quality standards of A.crispa. Method: Qualitative identification was made by characteristics of material medica

microscopic features and TLC. Moisture

total ash

acid-insoluble ash

and content of extract were determined with reference to the method in Chinese Pharmacopeia (2010 edition).The content of bergenin and ardisiacrispin A was determined by HPLC-ELSD. Result: Above mentioned method showed a strong specificity

the average content of water

total ash

acid-insoluble ash

alcohol-soluble extracts

bergenin and ardisiacrispin A from 12 batches of sample was 10.8%

2.5%

0.6%

17.8%

0.14%

0.28%.The method of quality control was established by according to the results of this experimental. Conclusion: This method is simple

rapid and reliable

suitable for the quality control of the drug.The method were establishment to control the quality of A.crispa.