Objective: To optimize purification technology conditions of tannin from Diascorea cirrhosa. Method: With the content and retention rate of tannin as indexes

different macroporous resin properties of absorption and desorption were observed by static absorption method

purification technology conditions of tannin from D. cirrhosa was optimized by single factor test and L9(34) orthgonal design. Result: AB-8 type macroporous resin was chosen

its optimum purification technology conditions were as followings:sample amount no more than 17.25 mg per gram of resin

washed impurity with 3 BV water

and eluted by 1.5 BV 40% ethanol with flow rate of 0.5 BV·h-1

collected the eluent.The content and retention rate of tannin were 82.02%

64.39%

respectively. Conclusion: This optimized technology was stable

feasible and reasonable

it could provide experimental basis for industrial purification of tannin in D. cirrhosa.