正交设计法优选舒肤爽喷雾剂中挥发油成分的CO超临界萃取工艺

程艳芹; 李明春; 李晓

doi:10.11653/zgsyfjxzz2013070063

您当前的位置：

首页 >

文章列表页 >

正交设计法优选舒肤爽喷雾剂中挥发油成分的CO超临界萃取工艺

更新时间：2024-01-04

- 正交设计法优选舒肤爽喷雾剂中挥发油成分的CO超临界萃取工艺
- Optimization of Supercritical CO Fluid Extraction Technology for Volatile Oil Components in Shufushuang Sprays by Orthogonal Design
- 中国实验方剂学杂志 2013年19卷第7期页码：63-65
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/zgsyfjxzz2013070063
  中图分类号：
- 纸质出版日期：2013
- 稿件说明：
移动端阅览
程艳芹, 李明春, 李晓. 正交设计法优选舒肤爽喷雾剂中挥发油成分的CO超临界萃取工艺[J]. 中国实验方剂学杂志, 2013,19(7):63-65.

CHENG Yan-qin, LI Ming-chun, LI Xiao. Optimization of Supercritical CO Fluid Extraction Technology for Volatile Oil Components in Shufushuang Sprays by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 63-65.
程艳芹, 李明春, 李晓. 正交设计法优选舒肤爽喷雾剂中挥发油成分的CO超临界萃取工艺[J]. 中国实验方剂学杂志, 2013,19(7):63-65. DOI： 10.11653/zgsyfjxzz2013070063.

CHENG Yan-qin, LI Ming-chun, LI Xiao. Optimization of Supercritical CO Fluid Extraction Technology for Volatile Oil Components in Shufushuang Sprays by Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(7): 63-65. DOI： 10.11653/zgsyfjxzz2013070063.

摘要

目的: 优选舒肤爽喷雾剂中蛇床子等4味药材的CO2超临界萃取工艺条件。方法: 以蛇床子素质量分数和总萃取得率为综合评价指标

采用HPLC测定蛇床子素含量

选取萃取压力、萃取温度及分离釜Ⅰ温度为考察因素

通过正交试验优选舒肤爽喷雾剂处方中4味药材的CO2超临界萃取工艺条件。结果: 萃取温度、萃取压力对萃取工艺有显著影响

分离Ⅰ温度无显著性影响。优选的萃取条件为萃取温度50 ℃

萃取压力30 MPa

分离釜Ⅰ温度50 ℃。结论: 优选的挥发油萃取工艺稳定可行

可推广使用。

Abstract

Objective: To optimize supercritical CO2 fluid extraction(CO2-SFE) conditions of four medicinal herbs in Shufushuang sprays including Cnidium monnieri

et al. Method: With the content of ostho1e and total extraction yield as comprehensive evaluation index

the content of osthole was determined by HPLC

CO2-SFE of four medicinal herbs in Shufushuang sprays was optimized by orthogonal design with extraction pressure

extraction temperature and the separating kettleⅠ temperature as factors. Result: Extraction pressure and temperature had significant effects on CO2-SFE

whereas the separating kettleⅠ temperature had no significant effects.Optimum CO2-SFE technology was A2B1C1

extraction pressure 30 MPa

extraction temperature 50 ℃

the separating kettleⅠ temperature 50 ℃. Conclusion: Optimized extraction technology of volatile oil was stable and feasible

it could be used in industrial production.

关键词

Keywords

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

用正交试验法对宣肺祛痰口服液中盐酸麻黄碱提取工艺的研究

正交设计优选抗瘤升白片的提取工艺

中药巴布剂制备工艺的实验研究

斑秃生发颗粒质量标准的研究

白头翁汤提取工艺试验研究