Objective: To establish the quality standard of Shudantong Granules. Method: The jasminoidin

rhein and tetrahydropalmatine in Shudantong Granules were identified by TLC

and the content of jasminoidin was detected by HPLC. The separation was carried out on an Agilent ZORBAX C18column (4.6 mm×250 mm

5 μm). The mobile phase consisted of acetonitrile-water (15: 85). The detective wavelength was set at 238 nm. The column temperature was kept at 30 ℃. The flow rate was 1.0 mL·min-1 and the injection volume was 10 μL. Result: The jasminoidin

rhein and tetrahydropalmatine could be identified by TLC and the calibration curve of jasminoidin showed a good linearity over the range of 15.1-151.0 mg·L-1 (r=0.999 9). The average recovery was 100.45% with RSD 0.48%. Conclusion: This method to identify three main ingredients in Shudantong Granules by TLC is simple and has a great repeatability. The negative control sample has no interference. The method to determine the content of jasminoidin in Shudantong Granules is rapid

accurate and its results have a good repeatability and recovery. This method can be used as the quality control method for this preparation.