Objective: To observe the therapeutic effect of Bufei addition and subtraction decoction in chronic obstructive pulmonary disease(COPD) a stable condition with the syndrome of qi deficiency of both lung and spleen with detected the expressions of clinical symptoms

physical signs

arterial blood gas

pulmonary function

tumor necrosis factor α(TNF-α)

interleukin 8(IL-8). Method: Dividing randomly sixty patients suffering from COPD in a stable condition with the syndrome of qi deficiency of both lung and spleen into 2 groups in even number named as treatment group and control group seperately. Detected the expressions of clinical symptoms

physical signs

arterial blood gas

pulmonary function

tumor necrosis factorα(TNF-α)

interleukin 8(IL-8)

before and after treatment. Result: After 2 months of treatment

both groups were markedly improve(P<0.05) in clinical symptoms. Pulmonary function had been up (P<0.05)

between the Jiajian Bufei decoction after treatment

and the expressions of the TNF-α

IL-8 were lower (P<0.05). The positive-controlled group patients had no obvious adverse reactions after treatment for 2 months. Compared with positive controlled group

the Jiajian Bufei decoction treatment group the expressions of TNF-α

IL-8 were markedly higher(P<0.05). Conclusion: The Yifei Jianpi method can improve the COPD patient's clinical symptoms

postpone the patient 's pulmonary function descend

improve living quality. Lowering content TNF-α

IL-8 into serum.