Objective: To investigate the clinical efficacy of treatment on the Qizhi Xueyu type lung cancer of Taohong Siwu soup plus and minus combined with chemotherapy. Method: The 60 cases of Qizhi Xueyu type lung cancer in middle and late period were randomly grouped to control group and treatment group

each group for 30 cases. The control groups were only used western medicine chemotherapy scheme

and the treatment groups were cured together with Taohong Siwu soup based on the treatment of control group. After 3 months' treatment continuously

to observe the short term curative effect

the improvement of life quality

the changes of body weight

the improvement of peripheral blood and immune function

and the occurrence of adverse reaction and the survival rates of patients after 1

3 and 5 years' treatment. Result: The total effectiveness of control group and treatment group were respectively 90.0% and 70.0%

the short term curative effect of treatment group was better than the control group

and there was significant difference(P<0.05); the improvement rate of life quality was respectively 60.0% and 40.0%

the treatment group was better than the control group

and there was significant difference(P<0.05);the improvement rate of body weight was respectively 16.67% and 16.67%

and there was no significant difference; the peripheral blood abnormality rates of treatment group were obviously lower than the control group

and there was significant difference(P<0.05);the treatment and control group were compared before and after treatment

the immune indexes (CD4+

CD8+

CD4+/CD8+ and the activity of NK cell) all presented significant difference of different degree(P<0.05 and P<0.01)

and the immunity of treatment group was obviously improved; compared with control group

the occurrence rate of adverse reaction of treatment group was obviously lower than control group

and there was significant difference(P<0.05). The survival rates of patients after 1

3 and 5 years' treatment was better than the control group

and there was significant difference(P<0.05). Conclusion: The Qizhi Xueyu type lung cancer was cured with Taohong Siwu soup plus and minus combined with chemotherapy

and it could effectively relieve the clinical symptoms

improve the immunity

reduce the occurrence of adverse reaction

and improve the life quality

and the TCM combined with chemotherapy had the efficacy improved and toxicity lowered

and it was worthy popularized and applied in clinic.