Objective: To establish quality standards of Baogan Jiangzhi granules. Method: TLC was used to identify Salviae Miltiorrhizae Radix et Rhizoma

Cyperi Rhizoma and Rhizoma Wenyujin Concisum in Baogan Jiangzhi granules.HPLC was adopted to determine contents of chlorogenic acid and salvianolic acid B with mobile phase of acetonitrile(A)-0.5% formic acid(B) gradient elution(0-10 min

10%A;10-20 min

10%-15%A;20-30 min

15%-20%A;30-53 min

20%-30%A;53-60 min

30%~10%A)

detection wavelength of these two ingredients were 327 and 286 nm

respectively. Result: Established TLC had clear spots without interference of the negative control sample.Linear ranges of chlorogenic acid and salvianolic acid B were 0.050 8-0.571 5 and 0.326-3.26 μg

average recoveries were 100.56%(RSD 2.00%) and 100.50%(RSD 1.59%)

respectively. Conclusion: These methods was accurate and specific

which were suitable for quality control of Baogan Jiangzhi granules.