Objective: The purpose is to discuss the clinical effects of Qufeng Runfei Tongluo Zhike decoction differentiation treatment on chronic cough and the influence of the decoction on patients'life quality. Method: Ninety cases of patients with chronic cough were randomly divided into control group (45 cases) and observation group (45 cases)according to the sequence of being in hospital.Both groups aimed at different pathogeny using corresponding treatment referred to'cough diagnosis and treatment guide'.For patients in control group

they took Baihe Guidingjin

6 g/time

3 times/day. Patients in observation group took Qufeng Runfei Tongluo Zhike decoction

1 does/day

conventional water frying and taken at twice.Treatment courses for two groups continued 2 weeks.Record day/night cough symptoms scores

expectoration et accompanied symptoms scores

cough extinction time and cough disappeared rate after treatment.Adopt Leicester cough questionnaire (LCQ) to evaluate cough life quality. Result: The total effective rate of the observation group was 90.6% superior to 80.0% of the control group(P<0.05)

after treatment

the integral of cough of daytime and night were both lower than than of the control group(P<0.01)

the integral of accompanied symptoms such as cough and the total symptom integral were both lower than of the control group(P<0.01)

the cough disappeared time of the observation group was (7.73±1.82) days were lower than (9.85±1.76) days of the control group (P<0.01)

the disappearance rate of cough was 44.44% superior to 22.22% of the control group(P<0.05)

the three dimension of LCQ scale such as physiological status

physiological health

society function and total grade were all higher than that of the control group(P<0.01). Conclusion: Qufeng Runfei Tongluo Zhike decoction which used in chronic cough can relief the main symptoms such as cough of the patients

improve quality of life of patients with cough

there was a significant clinical effect.