WANG Xiao-mei, WANG Xiao-qing, WANG Xin-lin, et al. Antioxidant Activities of Total Salvianolic Acid from [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(9): 162-165.
WANG Xiao-mei, WANG Xiao-qing, WANG Xin-lin, et al. Antioxidant Activities of Total Salvianolic Acid from [J]. Chinese journal of experimental traditional medical formulae, 2014, 20(9): 162-165. DOI: 10.13422/j.cnki.syfix.2014090162.
Objective: To determine the antioxidant activity of the total salvianolic acid from Salvia deserta Schang. Method: The extraction and purification of the salvianolic acid were prepared by using 40% ethanol extracted and macroporous adsorption resin purified respectively. The antioxidant activities of the extraction and purification of the total salvianolic acid were determined by·DPPH
·OH
O2-· scavenging experiments and Fe3+ reduction capacity experiments in vitro.Results were compared with that of positive control vitamin C (VC). Result: The·DPPH scavenging assay of the extraction and purification of the total salvianolic acid (IC500.029
0.039 g·L-1) were weaker than VC (IC50 0.018 g·L-1). The·OH scavenging assay (IC50 0.212
0.165 g·L-1) were higer than VC (IC50 0.356 g·L-1).The O2-·scavenging assay (IC50 3.735
1.913 g·L-1) were weaker than VC (IC50 0.390 g·L-1). The purificiation also has a certain reduction capacity. Conclusion: The total salvianolic acid from S. deserta possessed high antioxidant activity.