Studies on Pharmacodynamics and Pharmacokinetics of Anti endotoxin Shock of Shenmai Zhusheye (SMZ) in Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, (3): 22-25.
Studies on Pharmacodynamics and Pharmacokinetics of Anti endotoxin Shock of Shenmai Zhusheye (SMZ) in Rats[J]. Chinese journal of experimental traditional medical formulae, 2000, (3): 22-25. DOI: 10.13422/j.cnki.syfjx.2000.03.011.
Anti endotoxin shock effect being taken as observed index
pharmacodynamics and pharmacokinetics of SMZ were studied in rats. The results showed that SMZ could exhibit anti endotoxin shock effect in rats. Half life(T 1/2 =1 1849h) and pharmacokinetic equation (C=6 6636×e -0 5848t ) of SMZ were obtained with the dose effect and time effect relationships in rats.