NI Yan, HAO Xu-liang, LI Xian-rong. Quality Standard of Xiongzhizhentong Capsules[J]. Chinese journal of experimental traditional medical formulae, 2003, (5): 5-7.
NI Yan, HAO Xu-liang, LI Xian-rong. Quality Standard of Xiongzhizhentong Capsules[J]. Chinese journal of experimental traditional medical formulae, 2003, (5): 5-7. DOI: 10.13422/j.cnki.syfjx.2003.05.003.
芎芷镇痛胶囊质量标准的研究
摘要
目的 :建立芎芷镇痛胶囊质量控制方法。方法 :采用TLC对川芎、白芍、柴胡、人参进行定性鉴别
采用HPLC测定阿魏酸的含量。结果 :薄层图谱斑点清晰
阴性对照无干扰。含量测定阿魏酸在 0 10 2 5~ 0 5 12 5 μg间有良好的线性关系
回收率为 98 8%
RSD为 1 5 9%。结论 :方法可靠
结果稳定
重现性好。可作为该制剂的质量控制方法。
Abstract
Objective:To establish the quality standard for Xiongzhizhentong Capsules.Methods:Thin layer chromatography was used for simultaneous of Rhizoma chuanxiong
Radix Paeoniae Alba
Radix Bupleuri and Radix Ginseng.Ferulic acid was determined by HPLC.Results:The TLC sports developed were fairly clear
and the blank test showed no interference.The linearity for ferulic acid was obtained over the range of 0^1025~0.5125μg and the average recovery of ferulic acid was 98^8%.with RSD 1.59%.Conclusion:The method is reliable.The results are stable with good reproducible.It can be used for quality control of the capsules.