当归补血汤对急性缺氧小鼠红细胞功能的影响

陈云华; 孙建宁

doi:10.13422/j.cnki.syfjx.2006.10.019

您当前的位置：

首页 >

文章列表页 >

当归补血汤对急性缺氧小鼠红细胞功能的影响

更新时间：2024-09-23

- 当归补血汤对急性缺氧小鼠红细胞功能的影响
- The Effects of Danggui Buxue Tang on the Erythrocyte Function in the Acute Hypoxic Mice
- 中国实验方剂学杂志 2006年第10期页码：41-43
- 作者机构：
  
  1. 北京城市学院
  2. 北京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2006.10.019
  中图分类号： R285.5
- 纸质出版日期：2006
- 稿件说明：
移动端阅览
[1]陈云华,孙建宁.当归补血汤对急性缺氧小鼠红细胞功能的影响[J].中国实验方剂学杂志,2006(10):41-43.

CHEN Yun-hua~. The Effects of Danggui Buxue Tang on the Erythrocyte Function in the Acute Hypoxic Mice[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 41-43.
[1]陈云华,孙建宁.当归补血汤对急性缺氧小鼠红细胞功能的影响[J].中国实验方剂学杂志,2006(10):41-43. DOI： 10.13422/j.cnki.syfjx.2006.10.019.

CHEN Yun-hua~. The Effects of Danggui Buxue Tang on the Erythrocyte Function in the Acute Hypoxic Mice[J]. Chinese journal of experimental traditional medical formulae, 2006, (10): 41-43. DOI： 10.13422/j.cnki.syfjx.2006.10.019.

摘要

目的:研究当归补血汤对急性缺氧小鼠红细胞功能的影响。方法:将小鼠分成五组:正常组

对照组

当归补血汤20

5g/kg组。灌胃给水或药10d后制作急性缺氧模型。然后检测小鼠红细胞膜流动性、红细胞变形性与红细胞免疫功能。结果:当归补血汤5g/kg.d连续10d灌胃给药可预防急性缺氧引起红细胞膜流动性、红细胞变形性及红细胞免疫功能的降低。当归补血汤10g/kg.d

连续10d灌胃给药可对抗急性缺氧引起红细胞膜流动性、红细胞变形性的降低

当归补血汤20g/kg.d对各项指标未观察到明显影响。结论:当归补血汤有增强红细胞功能的作用

可能是该方能补气生血的机理之一。

Abstract

Objective:The effects of Danggui Buxue Tang（Chinese Angelica decoction for replenishing blood;DBT） on the erythrocyte functions were studied in the acute hypoxia mice.Methods:The mice were divided into five groups:control

model

and DBT with three dosages（20

5g/kg·d）.Water or DBT were administrated for 10 days.Acute hypoxia model was made by putting the mice into hermetical specimen bottles for 10 minutes.Then the erythrocyte membrane fluidity

the erythrocyte deformability and the erythrocyte immunity was tested.Results:DBT（5g/kg·d） could prevent the erythrocyte membrane fluidity from decreasing.The same actions were observed for the erythrocyte deformability and the erythrocyte immunity function in the acute hypoxia mice.DBT 10g/kg·d could prevent the erythrocyte membrane fluidity and the erythrocyte deformability from decreasing.However

effects were not observed with DBT 20g/kg.Conclusion:The above study shows that small and middle dose DBT can improve the function of red blood cell

which may be the mechanism of invigorating qi to promote blood of DBT.

关键词

Keywords

references

浏览量

255

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

HIF-1α在糖尿病肾病中的机制研究及中医药改善作用的研究进展

经典名方当归补血汤的药效物质基础和质量控制研究进展

当归补血汤对低流体剪切应力作用下内皮细胞功能损伤的保护作用

益气养阴逐瘀方对LPS诱导的RAW 264.7细胞炎症模型体外抗炎活性的影响