CHEN Xue-gong~. The Effect of DongMeiYin on Advanced Glycation end Products in the Renal Cortex of Early Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (1): 41-43.
CHEN Xue-gong~. The Effect of DongMeiYin on Advanced Glycation end Products in the Renal Cortex of Early Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (1): 41-43. DOI: 10.13422/j.cnki.syfjx.2007.01.017.
冬梅饮对早期糖尿病肾病大鼠肾组织非酶糖基化终产物的影响
摘要
目的:评价中药冬梅饮(DMY)对糖尿病大鼠非酶糖基化终产物(advanced glycation end products
Objective:To evaluate the effects of DongMeiYin(DMY) on advanced glycation end products(AGEs) in the diabetic rats
and investigate the mechanism of preventing and treating early diabetic nephropathy(DN).Methods:The rat early DN model was induced by injection of streptozotocin(STZ).The changes of the blood glucose
uA1b
uα
1
-MG and AGEs in the renal cortex and the effects of DMY were observed.Results:The blood glucose
uA1b
uα
1
-MG and AGEs of the model rats were obviously increased.DMY could decrease the parameters effectively.Conclusion:DMY could inhibits the AGEs and reduce the ua1b