LIU Zhi-bao, LAN Yan-yu~, WANG Yong-lin, et al. Effects of Different Extracts of Hongcao from Fufang Hongcao on Acute Myocardial Infarction in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (8): 21-24.
LIU Zhi-bao, LAN Yan-yu~, WANG Yong-lin, et al. Effects of Different Extracts of Hongcao from Fufang Hongcao on Acute Myocardial Infarction in Rats[J]. Chinese journal of experimental traditional medical formulae, 2007, (8): 21-24. DOI: 10.13422/j.cnki.syfjx.2007.08.010.
Objective:To compare Pharmacodynamics properties between the extracts of Hongcao
and determine an optimum technique to refine and purify.Methods:The acute myocardial infarction of rat was induced by ligating anterior branch of the left coronary artery.The change of ECG
and the level of CK
LDH were determined
the infarction area of myocardium was also observed.Results:N-butanol extracts of Hongcao could obviously decrease the elevated J of ECG
decrease the infarction area of myocardium
reduce the level of CK
LDH.Conclusion:Adopt n-butanol extraction can concentrate effective composition of Hongcao.