WANG Jing-xiang~1, LU Wen-wei~2, YU Jing~1, et al. Protective Effects of Total Flavones of Pollen Typhae on Acute Myocardial Ischemia Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, (1): 39-42.
WANG Jing-xiang~1, LU Wen-wei~2, YU Jing~1, et al. Protective Effects of Total Flavones of Pollen Typhae on Acute Myocardial Ischemia Dogs[J]. Chinese journal of experimental traditional medical formulae, 2008, (1): 39-42. DOI: 10.13422/j.cnki.syfjx.2008.01.021.
Objective:The protective effects of total flavones of Pollen Typhae on acute myocardial ischemia were investigated in dogs.Methods:Acute myocardial ischemia model was made by ligation of left anterior descending artery in the anesthetized open chest dogs.The effects of total flavones of Pollen Typhae on epicardium electrocardiogram(EECG)and myocardial infarction square(MIS) were measured
and effects on enzymology in serm were also determined.Results:Total flavones of Pollen Typhae can reduce the degree and scope of myocardial ischemia(∑-ST and N-ST)
and decrease myocardial infarction square.Moreover
it also can reduce FFA and LPO content in serum
and improve SOD and GSH-Px activity in acute myocardial dogs.Conclusions:Total flavones of Pollen Typhae have the protective effects on acute myocardial ischemia dogs.