Objective:To investigate the effect on angiogensis as well as tumor growth for the traditional Chinese medical astringent

such as

Cortex Ailanthi

and the mechanism of the effect.Method:A model of transplanting tumor in mice was used to study the effect of these medical herbs on tumor growth.The expression of Ⅷ-RAg and matrix metalloproteinase-9（MMP-9） in tumor tissue were examined with immunohistochemical method.The microvessel density（MVD） of the tumour tissue was also measured with the Image Pro Plus software.Result:Cortex Ailanthi could obviously inhibit the growth of sarcoma（S

180） transplanted subcutaneously in mice（P

<

0.05）.There were fewer vessels in sarcoma tissue in Cortex Ailanthi group than in control group and CTX group（P

<

0.05）.The expression of MMP-9 was lower in Cortex Ailanthi group than in control group（P

<

0.05）.Conclusion:Cortex Ailanthi can inhibit angiogensis in tumor tissue

and can also suppress the growth of sarcoma（S

180） transplanted in mice and the expression of MMP-9 in the sarcoma tissue.