Objective:To investigate the effects of salidroside on hemorheology of rats

platelet aggregation rate in vitro in rats

coagulation time（CT） and platelet count（PC） in mice.Methods: The model of acute blood stasis was established with high-molecular weight dextran

the parameters were tested

such as blood viscosity

fibrinogen and hematocrit（Hct） etc;the effects of salidroside on platelet aggregation rate of rats

CT and PC of mice were rest after pretreatment with salidroside for 5 days.Results: Salidroside(6

12

24 mg·kg

-1

) could effectively prevent the ascending of whole blood viscosity

plasma viscosity

fibrinogen and Hct in the acute blood stasis model.Salidroside at all doses could effectively decrease platelet aggregation rate;Salidroside(48.0

24.0 mg·kg

-1

) could prolong CT and has no effect on PC.Conclusion: The results suggest that salidroside improves the hemorheological parameters of rats with acute blood stasis

and salidroside has some effects on anticoagulation

while it has no effect on PC.