JIA De-xian1, JI Xiao-mei2, Wang Qian1, et al. Influence of Xiaokekang on Renal Function in Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(7): 57-59.
JIA De-xian1, JI Xiao-mei2, Wang Qian1, et al. Influence of Xiaokekang on Renal Function in Diabetic Nephropathy Rats[J]. Chinese journal of experimental traditional medical formulae, 2009, 15(7): 57-59. DOI: 10.13422/j.cnki.syfjx.2009.07.026.
blood urea nitrogen and glycosylated hemoglobin in diabetic nephropathy rats and treating effects of Xiaokekang.Methods: Streptozotocin(STZ) was abdominally administered and was feeded by high lipid diet to establish diabetic nephropathy model in rats.Animals were divided into three groups: model group
Xiaokekang treatment group and normal group.Changes in glycemia
serum lipids
serum creatinine
blood urea nitrogen were measured at the 8th
12th and 16th week after STZ injection.Glycosylated hemoglobin was measured at the 16th weeks after STZ injection.Results: Glycemia
serum lipids
serum creatinine were higher at the 8th
12th and 16th week compared with normal group.Serum creatinine was higher at the 12th and 16th week
and glycosylated hemoglobin was also highter than that of the normal group.Xiaokekang reduced these changes.Conclusion: Xiaokekang can reduce glycemia