珍珠滴丸组方合理性研究

王爱民; 李翠兵; 李勇军; 何迅; 黄勇; 王永林; 兰燕宇

doi:10.13422/j.cnki.syfjx.2010.04.038

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珍珠滴丸组方合理性研究

药理 | 更新时间：2024-09-23

- 珍珠滴丸组方合理性研究
- Study on the rationality of combination prescription of Pearl Dropping Pills
- 中国实验方剂学杂志 2010年16卷第4期页码：88-91
- 作者机构：
  
  贵阳医学院药学院
- 作者简介：
- 基金信息：
  
  国家科技支撑计划（2006BA106A01-03）
- DOI：10.13422/j.cnki.syfjx.2010.04.038
  中图分类号： R285.5
- 纸质出版日期：2010
- 稿件说明：
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[1]王爱民,李翠兵,李勇军,何迅,黄勇,王永林,兰燕宇.珍珠滴丸组方合理性研究[J].中国实验方剂学杂志,2010,16(04):88-91.

WANG Ai-min, LI Cui-bing, LI Yong-jun, et al. Study on the rationality of combination prescription of Pearl Dropping Pills[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 88-91.
[1]王爱民,李翠兵,李勇军,何迅,黄勇,王永林,兰燕宇.珍珠滴丸组方合理性研究[J].中国实验方剂学杂志,2010,16(04):88-91. DOI： 10.13422/j.cnki.syfjx.2010.04.038.

WANG Ai-min, LI Cui-bing, LI Yong-jun, et al. Study on the rationality of combination prescription of Pearl Dropping Pills[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(4): 88-91. DOI： 10.13422/j.cnki.syfjx.2010.04.038.

摘要

目的:研究珍珠滴丸的组方合理性。方法:以大鼠口腔黏膜溃疡愈合的药效学试验为评价指标

通过正交实验的交互作用和方差分析

探讨组方中各药味的主次及相互关系

用正交t值法实验设计进行处方配比研究。结果:各药物在珍珠滴丸组方中的重要性地位依次为:羊耳菊>甘草>冰片>珍珠;冰片与珍珠之间具有明显的交互作用

且4药合用具有协同效果;处方中羊耳菊、甘草、珍珠和冰片的比例为100∶20∶2∶1。结论:通过对组方及配比的合理性研究

确定了组方配比

同时验证了该方民间用药的合理性。

Abstract

Objective:To study the rationality of combination prescription of Pearl Dropping Pills.Method: The pharmacodynamic study on healing of oral ulcerative macous membrane in rats was used as evaluation index.The interaction and variance analysis of orthogonal design were employed to explore the primary-secondary and correlation of all herbs in combination prescription.The orthogonal t-value experiment was adopted to research the proportion of prescription.Result:The importance of each herb in combination prescription of Pearl Dropping Pills was appeared to be:herba Inulae cappae > licorice > borneol > pearl.The obvious interactions between borneol and pearl and the synergistic effect of four herbs had been found to exist.The proportion of herba Inulae cappae

licorice

borneol and pearl were 100∶ 20∶ 2∶ 1.Conclusion:The combination of Pearl Dropping Pills is established and the rationality of the folk medicine is verified by this experimental study.

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