Objective:To investigate the effects of Shenmai injection on perioperation T-lymphocyte subsets and natural killer cells for patients received cervical cancer. Method: 68 patients with cervical cancer were randomly divided into two groups

34 patients were in each group. Shenmai group was received 50 mL Shenmai injection diluted with 300 mL 5% glucose 1 day before operation until 7 day after operation

and control group was received only 300 mL 5% glucose. Peripheral venous blood samples were taken before operation（ T1）

the end of operation（T2） and the seventh day after operation（T3） for determination of CD3 + 、CD4 + 、CD8 + 、CD4 + /CD8 + and NK. Result: The CD3 + 、CD4 + 、CD8 + 、CD4 + /CD8 + and NK were decreased in both groups at the end of operation （P < 0. 05 or P < 0. 01）. On the seventh postoperation day

the CD3 + 、CD4 + 、CD8 + 、CD4 + /CD8 + and NK were returned to preoperational levels in both groups

but there was a significant change between the two groups（ P < 0. 01）. Conclusion: Shenmai injection can improve the inhibition effects because of operation

and promote to recover the immunologic function for patients received cervical cancer.