异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察

朱黎明

doi:10.13422/j.cnki.syfjx.2010.05.083

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异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察

临床 | 更新时间：2024-09-23

- 异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察
- Treatment of Cyst Jialing River Acne with Isotretinoin Soft Capsule Combined with Qing-gan Qu-cuo Recipe
- 中国实验方剂学杂志 2010年16卷第5期页码：211-213
- 作者机构：
  
  河南省洛阳市机车医院中西医结合科
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2010.05.083
  中图分类号： R758.733
- 纸质出版日期：2010
- 稿件说明：
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[1]朱黎明.异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察[J].中国实验方剂学杂志,2010,16(05):211-213.

ZHU Li-ming. Treatment of Cyst Jialing River Acne with Isotretinoin Soft Capsule Combined with Qing-gan Qu-cuo Recipe[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 211-213.
[1]朱黎明.异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察[J].中国实验方剂学杂志,2010,16(05):211-213. DOI： 10.13422/j.cnki.syfjx.2010.05.083.

ZHU Li-ming. Treatment of Cyst Jialing River Acne with Isotretinoin Soft Capsule Combined with Qing-gan Qu-cuo Recipe[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(5): 211-213. DOI： 10.13422/j.cnki.syfjx.2010.05.083.

摘要

目的:观察和研究异维A酸胶丸（泰尔丝）联合清肝祛痤方治疗囊肿聚合性痤疮的临床疗效。方法:50例囊肿聚合性痤疮患者随机分为两组

均给予异维A酸胶丸（泰尔丝）每次20mg

每天2次口服。治疗组（n=30）在此基础上加用清肝祛痤方

每日1剂

早晚分服

于治疗初始和2

8周时观察评价皮损改善

不良反应及16周时的复发情况。结果:治疗组有效率90.0%

对照组有效率45.0%。治疗组总皮损均数、炎症性皮损均数、非炎症性皮损均数治疗8周后与治疗前比较

差异有统计学意义（P<0.05或P<0.01）。对照组总皮损均数、炎症性皮损均数治疗8周后与治疗前比较

差异有统计学意义（P<0.05或P<0.01）

非炎症性皮损均数治疗8周后与治疗前比较

差异无统计学意义（P>0.05）。治疗组治疗8周后总皮损均数、非炎症性皮损均数与对照组相比较

差异有统计学意义（P<0.05或P<0.01）

炎症性皮损均数治疗后两组比较差异无显著性（P>0.05）。结论:异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮疗效肯定

复发率低且不良反应少。

Abstract

Objective:To observe and study Isotretinoin soft capsules （TaiErSi） combined with Qing-gan Qu-cuo recipe in treating cyst jialing river acne. Method:50 patients cyst jialing river acne patients were randomly divided into two groups

Isotretinoin soft capsules （TaiErSi） 20mg

2 times every day. The treatment group （ n = 30） was added with qing-gan qu-cuo recipe daily. In the treatment of initial and 2

8 weeks

observing and studying the lesions’ recovery

assessing skin evaluation for 16 weeks and adverse reaction of recurrence. Result: The efficiency of treatment group and control group was 90. 0% vs 45. 0% . Total skin lesions means

inflammatory lesions means and noninflammatory lesions means of treatment group 8 weeks after treatment with before treatment

were statistically significant difference （P < 0. 05 or P < 0. 01）. The control group’s total skin lesions means and inflammatory skin lesions means of 8 weeks after treatment compared with before treatment were statistically significant differente （P < 0. 05 or P < 0. 01）

the noninflammatory lesions means of control group before and after treatment were no significant differente （ P > 0. 05 ）. 8 weeks after treatment

total skin lesions means and noninflammatory skin lesions means of treatment group are better than those of control group significantly（P < 0. 05 or P < 0. 01）

the inflammatory lesions means of both groups 8 weeks after treatment were no statistically significant difference between the two groups （P > 0. 05）. Conclusion:Isotretinoin soft capsules combined with qing-gan qucuo recipe in treating Cyst jialing river acne has reliable effect

low recurrent rate and less adverse reactions.

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异维A酸胶丸联合清肝祛痤方治疗囊肿聚合性痤疮的临床观察