As an important active ingredient of liquorice

glycyrrhizin has anti-virus

anti-inflammatory

anti-allergy

anti allergy

anti-tumor and immunomodulatory effects.Which concern the role of immune regulation.Glycyrrhizin play a double role on cellular immunity and humoral immunity.Glycyrrhizin is an effective biological response modifier

the performance of the immune regulation in the immune active cells

cytokines

complement.Glycyrrhizin can enhance the helper T lymphocyte proliferation and activity

the promotion of lymphocytes IL-2

INF-γ

IL-1 and other cytokines

inhibition of IL-4

IL-10

IL-8

etc.It also has anti-complement activity

selectively inhibiting the activation of the complement system approach.Because of the immunomodulatory effects

glycyrrhizin has been widely used in clinical practice.In psoriasis

chronic idiopathic urticaria

bronchial asthma

chronic liver disease

AIDS and cancer and other diseases as the main drug treatment achieved good results.The immunomodulatory effects of glycyrrhizin is reviewed in this paper according to the investigation of the world.