消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响

徐慧军; 孙明娥; 纪令士; 张婧婧

doi:10.13422/j.cnki.syfjx.2010.06.094

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消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响

药理 | 更新时间：2024-09-23

- 消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响
- Influence and of Endometriosis Model Mouse’s Liquid of Abdominal Cavity PGF_2α and Serum CA₁₂₅ Which Treated with Xiaozheng Decoction
- 中国实验方剂学杂志 2010年16卷第6期页码：211-214
- 作者机构：
  
  1. 青岛市海慈医疗集团妇科
  2. 青岛市海慈医疗集团检验中心
- 作者简介：
- 基金信息：
  
  青岛市中医科研基金项目（2009-zyy008）
- DOI：10.13422/j.cnki.syfjx.2010.06.094
  中图分类号： R711.71
- 纸质出版日期：2010
- 稿件说明：
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[1]徐慧军,孙明娥,纪令士,张婧婧.消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响[J].中国实验方剂学杂志,2010,16(06):211-214.

XU Hui-jun, SUN Min-e, JI Ling-shi, et al. Influence and of Endometriosis Model Mouse’s Liquid of Abdominal Cavity PGF_2α and Serum CA₁₂₅ Which Treated with Xiaozheng Decoction[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 211-214.
[1]徐慧军,孙明娥,纪令士,张婧婧.消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响[J].中国实验方剂学杂志,2010,16(06):211-214. DOI： 10.13422/j.cnki.syfjx.2010.06.094.

XU Hui-jun, SUN Min-e, JI Ling-shi, et al. Influence and of Endometriosis Model Mouse’s Liquid of Abdominal Cavity PGF_2α and Serum CA₁₂₅ Which Treated with Xiaozheng Decoction[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(6): 211-214. DOI： 10.13422/j.cnki.syfjx.2010.06.094.

摘要

目的:探讨消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素（PGF2α）和血清卵巢癌表面抗原（CA125）的影响。方法:实验分为生理盐水组

西药对照组

中药高剂量组

中药低剂量组

每组10只

采用ELISA法

观察子宫内膜异位症模型大鼠腹腔液PGF2α血清CA125水平浓度。结果:消癥汤能够降低子宫内膜异位症模型鼠血清CA125水平和腹腔液中PGF2α含量

对异位子宫内膜具有一定的抑制作用。结论:消癥汤能降低血清CA125水平、腹腔液中PGF2α含量

抑制异位子宫内膜的异常增生。

Abstract

Objective:To observe the effect of Xiaozheng Decoction（XZD） resolve in treating endometriosis model mouse and to explore its Liquid of abdominal cavity PGF2α、serum CA125.Method:Divide into four groups

the group treated with physiological saline

the group treated with Western medicine

the group treated with traditional Chinese medicine of high dosage

and the group treated with traditional Chinese medicine of low dosage

each group with ten mouses.By ELISA to observe endometriosis model mouse’s serum CA125andliquid of abdominal cavity PGF2α.Result:XZD reduce the serum CA125

liquid of abdominal cavity PGF2α

of endometriosis model mouse and has some restrained function for endometriosis.Conclusion:XZD has an effect may be achieved by reducing the serum CA125

liquid of abdominal cavity PGF2α

restraining unusual proliferation of endometriosis.

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消癥汤对子宫内膜异位症模型大鼠腹腔液前列腺素和血清卵巢癌表面抗原水平的影响