20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析

周正礼; 李峰; 胡平

doi:10.13422/j.cnki.syfjx.2010.11.022

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20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析

化学与分析 | 更新时间：2024-09-23

- 20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析
- GC/MS Fingerprints and Fisher Discrimination Analysis on Water-soluble Sugar from 20 Chinese Herbs with Cold and Heat Properties
- 中国实验方剂学杂志 2010年16卷第11期页码：41-44
- 作者机构：
  
  1. 山东中医药大学药学院
  2. 山东大学公共卫生学院
- 作者简介：
- 基金信息：
  
  国家重点基础研究发展计划（973计划）(2014CB543003)
- DOI：10.13422/j.cnki.syfjx.2010.11.022
  中图分类号： R284.1
- 纸质出版日期：2010
- 稿件说明：
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[1]周正礼,李峰,胡平.20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析[J].中国实验方剂学杂志,2010,16(11):41-44.

ZHOU Zheng-li1, LI Feng1, HU Ping2. GC/MS Fingerprints and Fisher Discrimination Analysis on Water-soluble Sugar from 20 Chinese Herbs with Cold and Heat Properties[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 41-44.
[1]周正礼,李峰,胡平.20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析[J].中国实验方剂学杂志,2010,16(11):41-44. DOI： 10.13422/j.cnki.syfjx.2010.11.022.

ZHOU Zheng-li1, LI Feng1, HU Ping2. GC/MS Fingerprints and Fisher Discrimination Analysis on Water-soluble Sugar from 20 Chinese Herbs with Cold and Heat Properties[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 41-44. DOI： 10.13422/j.cnki.syfjx.2010.11.022.

摘要

目的:探讨中药寒热药性与水溶性糖的相关性

进一步阐明中药四性与物质基础的关系。方法:选取10种寒性中药和10种热性中药

提取水溶性糖

分别加入盐酸羟胺、吡啶和乙酸酐进行乙酰化反应

测定水溶性糖的GC/MS指纹图谱

利用Fisher方法建立判别函数

分析实验结果。结果:Fisher判别函数实现了对20种中药寒热药性的准确识别

组内回代一致率为100%。结论:Fisher可以作为判别中药寒热药性与水溶性糖关系的统计学工具

水溶性糖是中药寒热药性的物质基础之一。

Abstract

Objecive:To discuss the relationship between water-soluble sugar and cold-heat properties and further reveal correlations of four properties and material basis.Method:Water-soluble sugars were purified from 10 herbs with cold properties and 10 herbs with heat properties.After acetylation

GC /MS fingerprints of water-soluble sugars were determined and the results were analyzed by Fisher.Result:Discriminant function had been established by Fisher.The Fisher discriminant analysis could distinguish the cold and heat properties between 20 herbs that the back substitution in group was 100%.There was difference between the drugs with cold and heat properties in the GC /MS fingerprints

which corresponded to the different water-soluble sugars in the cold and heat herbs.Conclusion:The Fisher analysis could differentiate the herbs with cold and heat properties

and it was an effective statistical tool to study the relationship between the cold and heat properties by water-soluble sugar.It concludes that the water-soluble sugar is one of the material basis of four properties of herbs.

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20种中药水溶性糖GC/MS指纹图谱与寒热药性的Fisher判别分析