LI Shu-wen1, WU Qing-he2, HUANG Ping2, et al. Experimental Study of Suoquan Capsule on Renin-Angiotensin-Aldosterone System in Rats with Diuresis and Deficiency of Kidney[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 108-110.
LI Shu-wen1, WU Qing-he2, HUANG Ping2, et al. Experimental Study of Suoquan Capsule on Renin-Angiotensin-Aldosterone System in Rats with Diuresis and Deficiency of Kidney[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 108-110. DOI: 10.13422/j.cnki.syfjx.2010.11.038.
Objective:To expound the mechanism of nourishing kidney and reducing urine by investigating the regulative action for renin-angiotensin-aldosterone system(RAAS) by Suoquan Capsule.Method:The rat model of kidney deficiency and diuresis was established by adenine.The levels of ACE
PRA
AngⅡ and ALD in blood were determined for model group
Suoquan Capsule group
Jinsuo Gujin Wan group and control group with ELISA technology.Result:Compared with model group
Suoquan Capsule could remarkedly increase the levels of ACE
PRA
AngⅡ and ALD in blood of the rats with kidney deficiency and diuresis.Conclusion:Suoquan Capsule can regulate water metabolism by coordinating the function of RAAS.The mechanism of nourishing the kidney and reducing urine by Souquan Capsule appears to be related with endocrinium system.