GUO Jie1, ZHAO Hai-xia2, YAN Yan1, et al. Effect of Sulfur Fumigated Dioscorea opposita on Oxidative Stress and ATP Enzyme in Liver of Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 150-153.
GUO Jie1, ZHAO Hai-xia2, YAN Yan1, et al. Effect of Sulfur Fumigated Dioscorea opposita on Oxidative Stress and ATP Enzyme in Liver of Rats[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(11): 150-153. DOI: 10.13422/j.cnki.syfjx.2010.11.048.
Objective:To investigate the influence of Sulfur fumigated Dioscorea opposita on antioxidation
Ca2 + Mg2 +-ATPase
Na + K +-ATPase in liver of rats.Method:Wistar rats were divided randomLy into 4 groups
one control and three experimental groups administrated diets mixed with concentrated extractions from unfumigated
commercial and sulfur fumigated D.opposita respectively.The activities of Ca2 + Mg2 +-ATPase and Na + K +-ATPase and the level of MDA and activities of SOD and GSH-Px 14 weeks after treatment were measured and observe liver framework of organization change.Result:Results showed that activities of GSH-Px 14 weeks after treatment of un-fumigated
commercial D.opposita were significantly increased compared with control group;commercial D.opposi-ta enhanced the activities of Na + K +-ATPase.Conclusion:The long-term use of D.opposita has the possibility to cause lipid peroxidation and change the activities of Na + K +-ATPase in liver.