LIU Li1, MU Xiao-min2, SHEN Yi-miao1, et al. Study on Extracting Technology for Xuefu-Chuanping Gel Patch[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 4-6.
LIU Li1, MU Xiao-min2, SHEN Yi-miao1, et al. Study on Extracting Technology for Xuefu-Chuanping Gel Patch[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 4-6. DOI: 10.13422/j.cnki.syfjx.2010.12.004.
穴敷喘平凝胶贴剂提取工艺研究
摘要
目的:优选穴敷喘平凝胶贴剂的最佳提取工艺。方法:采用正交试验设计法
以浸膏得率和盐酸麻黄碱含量为评价指标
考察乙醇体积分数
乙醇用量
提取时间3个因素对浸膏得率及有效成分的影响
优选最佳提取工艺。结果:影响提取效果的因素顺序为:乙醇体积分数>乙醇用量>提取时间
乙醇体积分数对提取有显著性影响。结论:优选得到的穴敷喘平凝胶贴剂的最佳提取工艺为
加70%乙醇8倍量
提取2次
每次1 h。
Abstract
Objective: To optimize the extracting technology of Xuefu-Chuanping gel patch.Method: Orthogonal Design was used to optimize extracting technology of Xuefu-Chuanping gel patch with the concrete yield and the content of ephedrina hydrochloridum as judgement criterias.Three factors were investigated including the alcoholic concentration
alcoholic volume and extracting time.Result: The order of the factors which affected extracting was: concentration of ethanol > dosage of solvent > extraction time.And the concentration of ethanol had significant effect.Conclusion: The optimal extracting technology was to reflux the herb for two times
one hour each time with 8 times amount of 70% alcohol.