YANG Hua-sheng, ZHANG Kun, YING Xiao-ying, et al. Optimization Investigation of Extraction Technology of Apocynum Delayed Pulse-release Tablet by Orthogonal Test with Multi-targets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 14-16.
YANG Hua-sheng, ZHANG Kun, YING Xiao-ying, et al. Optimization Investigation of Extraction Technology of Apocynum Delayed Pulse-release Tablet by Orthogonal Test with Multi-targets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 14-16. DOI: 10.13422/j.cnki.syfjx.2010.12.007.
多指标正交试验优选罗布麻定时脉冲片提取工艺
摘要
目的:对罗布麻定时脉冲片进行提取工艺优选。方法:以金丝桃苷、总黄酮和浸膏得率为检测指标
采用多指标正交试验法进行提取工艺研究
得罗布麻定时脉冲片的最佳提取工艺。结果:罗布麻定时脉冲片最优提取工艺为:罗布麻叶加水提取2次
第1次加入10倍量水回流提取2.0 h
第2次加入8倍量水回流提取1.5 h。结论:多指标正交试验可用于罗布麻定时脉冲片提取工艺优化
为罗布麻定时脉冲片的制剂研究提供理论依据。
Abstract
Objective: To optimize the extraction technology of Apocynum delayed pulse-release tablet.Method: With the indicators of hyperin
flavonoids and extract yield
orthogonal test was carried out to achieve the best extraction technology of Apocynum delayed pulse-release tablet by the multiple guidelines grading method.Result: The best extraction technology was to extract for two times
the first time was to extract for 1.5 h with 10 fold water and the second time was to extract for 1.0 h with 8 fold water.Conclusion: The multiple guidelines grading method can be used to optimize the extraction technology for Apocynum delayed pulse-release tablet
and it provides a theoretical basis for its preparation.