生地黄汤不同制备方法多糖含量变化及止血作用

王梅; 张丽娟; 李瑾; 焦媛媛; 郭东艳

doi:10.13422/j.cnki.syfjx.2010.12.035

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生地黄汤不同制备方法多糖含量变化及止血作用

药理 | 更新时间：2024-09-23

- 生地黄汤不同制备方法多糖含量变化及止血作用
- Experimental Study on Change of Content of Polysaccharides and Hemostatic Effect in Shengdihuang Decoction with Different Preparation Methods
- 中国实验方剂学杂志 2010年16卷第12期页码：115-117
- 作者机构：
  
  1. 陕西中医学院附属医院制剂中心
  2. 陕西中医学院药学院
- 作者简介：
- 基金信息：
  
  陕西省科技厅资助项目（2008K16-04;SJ08C239）
- DOI：10.13422/j.cnki.syfjx.2010.12.035
  中图分类号： R284;R285
- 纸质出版日期：2010
- 稿件说明：
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[1]王梅,张丽娟,李瑾,焦媛媛,郭东艳.生地黄汤不同制备方法多糖含量变化及止血作用[J].中国实验方剂学杂志,2010,16(12):115-117.

WANG Mei1, ZHANG Li-juan2, LI Jin2, et al. Experimental Study on Change of Content of Polysaccharides and Hemostatic Effect in Shengdihuang Decoction with Different Preparation Methods[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 115-117.
[1]王梅,张丽娟,李瑾,焦媛媛,郭东艳.生地黄汤不同制备方法多糖含量变化及止血作用[J].中国实验方剂学杂志,2010,16(12):115-117. DOI： 10.13422/j.cnki.syfjx.2010.12.035.

WANG Mei1, ZHANG Li-juan2, LI Jin2, et al. Experimental Study on Change of Content of Polysaccharides and Hemostatic Effect in Shengdihuang Decoction with Different Preparation Methods[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(12): 115-117. DOI： 10.13422/j.cnki.syfjx.2010.12.035.

摘要

目的:研究生地黄汤不同制备方法多糖含量变化及对止血作用的影响。方法:以葡萄糖为对照品采用蒽酮-硫酸法于622 nm处测定沉淀中多糖的含量;采用剪尾法及毛细玻管法测定各组小鼠出、凝血时间

与对照组进行比较

并进行统计学处理。结果:分煎组和加粉组的止血效果相近且好于合煎组。分煎组和加粉组的含糖量也相近且远远大于合煎组。结论:生地黄汤的止血作用与多糖含量成正相关关系。

Abstract

Objective: To study the change of the content of polysaccharides and hemostatic effect in Shengdihuang decoction with different preparation methods.Method: Anthrone-sulfuri acid colorinetric methods were used;the mice were administered with different proportion methods in Shengdihuang decoction

ig.Breaking tail hemostasia and capillary coagulation in mice were used to evaluate the hemostatic effect.Compared with the control group

and statistically analyzed.Result: The hemostatic effect of separated group was similar to the group of powder’s

but their effect was better than integrated group’s.The content of polysaccharides in the separated group was similar to the group of powder’s

but their content of polysaccharides was higher than the integrated group’s.Conclusion: The hemostatic effect is proportionate to the content of polysaccharides.

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