WANG Yue-fei, ZHAO Hong-ye, WANG Yu-ge, et al. Effect of Bioconversion Product of Jade Screen Powder on Cellular Immunity in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 176-178.
WANG Yue-fei, ZHAO Hong-ye, WANG Yu-ge, et al. Effect of Bioconversion Product of Jade Screen Powder on Cellular Immunity in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 176-178. DOI: 10.13422/j.cnki.syfjx.2010.14.013.
Objective:To observe the effect of the bioconversion product of jade screen powder on cellular immunity in immunosuppressed mice.Method:The levels of CD4 + T
CD8 + T
CD4 + T/CD8 + T were determined by flow cytometry;The content of serum interleukin-2(IL-2) and interferon-γ(IFN-γ) were detected by ELISA.Result:Compared with cyclophosphamide group
the levels of CD4 + T
CD8 + T
CD4 + T/CD8 + T improved in experimental group(P < 0.01 or P < 0.05) and the content of serum IL-2 and IFN-γ improved obviously in experimental group(P < 0.01).Conclusion:The bioconversion product of Jade Screen Powder can promote the cell immunity function
through regulating the balance between CD4 + T and CD8 + T cells and correcting Th1/Th2 drift phenomenon to keep the superiority of Th1.