Objective:To establish the quality standard for Niaoganning Granule.Method:The TLC was applied to identify Herba Glechomae Longitubae and Herba Pteridis Nervosae in this prescription

and aesculetin content in Herba Violae was determined by HPLC.A column（4.6 mm × 250 mm

5 μm） was used with the mobile phase of methanol and 0.5% phosphoric acid（22∶ 78） at the detection wavelength of 345 nm.Result:Glechomae Longitubae and Pteridis Nervosae could be identified by TLC.The aesculetin linear rang of 20.08-2 080 ng

and the average recoverywas 96.3%

RSD 1.9%

Conclusion:The above methods are simple

sensitive

accurate and re-producible

and can be used for the quality control of this granule.