甘草废渣中甘草黄酮提取工艺研究

马子娇; 许颖; 刘佳; 赵永雪; 贾永亮; 倪京满

doi:10.13422/j.cnki.syfjx.2010.15.007

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甘草废渣中甘草黄酮提取工艺研究

工艺与制剂 | 更新时间：2024-09-23

- 甘草废渣中甘草黄酮提取工艺研究
- Study on Extraction Process of Licorice Flavonoids from Licorice Waste Residue
- 中国实验方剂学杂志 2010年16卷第15期页码：15-19
- 作者机构：
  
  兰州大学药学院药物制剂研究所
- 作者简介：
- 基金信息：
  
  甘肃省自然科学基金（0803RJZA079）;甘肃省中医药重点项目基金（GZK-2009-1）
- DOI：10.13422/j.cnki.syfjx.2010.15.007
  中图分类号： R284.1
- 纸质出版日期：2010
- 稿件说明：
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[1]马子娇,许颖,刘佳,赵永雪,贾永亮,倪京满.甘草废渣中甘草黄酮提取工艺研究[J].中国实验方剂学杂志,2010,16(15):15-19.

MA Zi-jiao, XU Ying, LIU Jia, et al. Study on Extraction Process of Licorice Flavonoids from Licorice Waste Residue[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 15-19.
[1]马子娇,许颖,刘佳,赵永雪,贾永亮,倪京满.甘草废渣中甘草黄酮提取工艺研究[J].中国实验方剂学杂志,2010,16(15):15-19. DOI： 10.13422/j.cnki.syfjx.2010.15.007.

MA Zi-jiao, XU Ying, LIU Jia, et al. Study on Extraction Process of Licorice Flavonoids from Licorice Waste Residue[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 15-19. DOI： 10.13422/j.cnki.syfjx.2010.15.007.

摘要

目的:研究从甘草废渣中优化得到提取甘草黄酮最佳工艺条件

探讨甘草废渣开发利用的可行性。方法:采用有机溶剂热回流法、超声辅助有机溶剂热回流法、碱性溶剂提取法、超声辅助碱性溶剂提取法来提取甘草废渣中的甘草黄酮

根据正交试验的产率、含量和α-葡萄糖苷酶抑制活性

优化甘草黄酮的提取工艺条件。结果:超声辅助有机溶剂热回流法为最佳方法

最佳提取条件是65%乙醇

料液比1∶12

提取时间1.5 h

提取温度75℃。结论:开发和利用甘草废渣提取甘草黄酮具有的可行性

具有较好的社会效益和经济效益。

Abstract

Objective:Study the optimum condition of extraction of licorice flavonoids from licorice waste residue and explore the feasibility of development and utilization of licorice waste residue.Method:Organic solvent extraction

ultrasonic-assisted organic solvent extraction

basic solvents extraction and ultrasonic-assisted basic solvent extraction were used to extract licorice flavonoids from licorice waste residue.Optimum condition for extraction was selected with theorthogonal design

using the yield

content and α-glucosidase inhibitory activity of licorice flavonoids from all extracts as the evaluating criteria.Result: The optimum extracting condition with ultrasonic-assisted organic solvent extraction method was that the ethanol concentration was 65%

ratio of material to solvent was 1∶ 12

extraction time was 1.5 h

and extraction temperature was at 75 ℃.Conclusion:The development and utilization of extracting licorice flavonoids from licorice waste residue was feasible with good social and economic benefits.

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