LEI Yang, XIA Xin-hua, CHEN Xi. Study on Acohol Extraction Process of Weikan Tablets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 28-30.
LEI Yang, XIA Xin-hua, CHEN Xi. Study on Acohol Extraction Process of Weikan Tablets[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(15): 28-30. DOI: 10.13422/j.cnki.syfjx.2010.15.018.
正交设计优选胃康片醇提工艺
摘要
目的:探索胃康片最佳醇提工艺条件。方法:以浸膏得率和盐酸小檗碱含量为评价指标
采用正交设计法对醇提工艺条件进行优选。结果:最佳提取工艺为:以80%乙醇为溶剂
浸泡1.5 h
提取2次
加醇量分别为8
6倍量
提取时间分别为2.5
2.0 h。结论:优选的提取工艺稳定可行。
Abstract
Objective: To seek the optimum alcohol extraction conditions of Weikan tablets.Method:The extraction conditions were optimized by orthogonal tests with the extract yield and the amount of the extracted hydrochloride berberine as index.Result: The optimum extraction process was as follows: soaking in alcohol for 1.5 h
extracting two times
adding alcohol for 8
6 times and extracting for 2.5
2.0 h respectively.Conclusion: The optimum extraction process was stable and practicable in manufacture.