Objective:To study

the effect of decoction of Agastache rugosa with dried tangerine peel in different proportion on gastrointestinal motility in rat model of limb ischemia-reperfusion.Method:Limb ischemiareperfusion model of gastrointestinal dysfunction was established.Decoction of Agastache rugosa with tangerine peel in different proportions was administered to observe the influence on gastrointestinal motility in ischemia-reperfusion rat and on gastrointestinal hormone abnormalities.Result:Gastrointestinal motility in the model rat was slowed down

and secretion of motilin and gastrin was decreased.Agastache rugosa and dried tangerine peel together in different proportions could improve gastrointestinal mobility in the model（P < 0.05） and increase the levels of the motilin and gastrin（P < 0.05）.Conclusion:Agastache rugosa and dried tangerine peel together in different proportions may improve gastrointestinal motility disorder in the brat model of limb ischemia-reperfusion.The mechanism may linked with improvement of gastrointestinal motility

and the increase in plasma motilin and gastrin.