REN Yong-shen1, ZHANG Ping1, YAN Dan1, et al. Study on Protective Effect of Yinzhihuang Injection on Hepatic Cell Damage Caused by Carbon Tetrachloride in vitro[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 115-117.
REN Yong-shen1, ZHANG Ping1, YAN Dan1, et al. Study on Protective Effect of Yinzhihuang Injection on Hepatic Cell Damage Caused by Carbon Tetrachloride in vitro[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 115-117. DOI: 10.13422/j.cnki.syfjx.2010.18.017.
Objective:To study the protective effect of Yinzhihuang Injection on hepatic cell damage caused by Carbon tetrachloride(CCl4) in vitro.Method: CCl4 fumigation method was adopted to duplicate hepatic cell damage in vitro
and the protective effect of Yinzhihuang Injection and Fufang Yinchen Injection and their main active ingredients
baicalin and coumarin
from different companies were investigated.Result:The ALT
AST and MDA of damaged cells could be decreased and GSH-Px could be elevated by Yinzhihuang Injections from different factories
and the strongest protective effect was originated by Fufang Yinchen Injection.Conclusion: Both Yinzhihuang Injection and their main active ingredients
baicalin and coumarin
could prevent the hepatic cell damage caused by CCl4 in vitro
and the protective effect of normal samples from different companies had good consistency agreed with each other.