ZENG Qun, ZHAO Guo-yi. Experiment Research of Shutong Capsule on Defecating Function with Coprostasis Type of Dry Stagnation in Stomach and Intestines[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 139-141.
ZENG Qun, ZHAO Guo-yi. Experiment Research of Shutong Capsule on Defecating Function with Coprostasis Type of Dry Stagnation in Stomach and Intestines[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(18): 139-141. DOI: 10.13422/j.cnki.syfjx.2010.18.023.
Objective:To study the effect of Shutong Capsule on defecating function with type of dry stagnation in stomach and intestines.Method: Through feeding with rice and prohibition of drinking water three days
we prepared the rat model and mouse model with coprostasis type of dry stagnation in stomach and intestines.And then
using Shutong Capsule(high
medium and low dosage
ig) as the treatment
first time of defecation and grains of defecation in 4 h for normal mice and dry stool constipation mice
and periotalsis of intestine for normal rats and dry stool constipation rats were all observed and recorded.Result:There were no impact on purgation for normal mice and rat.There were significant differences between all the drug groups and model group in first time of defecation and grains of defecation in 4 h of mice(P < 0.01 or P < 0.05).The effect of Shutong high
medium dosage group was more evident than that in the low one(P < 0.001).Shutong high
medium dosage group were significantly increased comparing with model group in the pushing length and percentage of rat intestine(P < 0.001 or P < 0.01).Conclusion:Shutong Capsule can moisten intestines and urge purgation
increase the peristalic rate of intestine for type of dry stagnation in stomach and intestines.