Objective:The solid phase extraction and capillary gas chromatography were introduced for de-termining 12 organoehiorine and pyrethroid pesticide residues in polygonum orientale.Method:The organochlorine and pyrethroid pesticides were extracted with n-hexane and acetone by ultrasonic method and cleaned up by Florisil solid-phase extraction（SPE） column.Then

the extract was separated by capillary column HP-5（0.32 mm × 30 m

0.25 μm） and detected by（electron capture detector

ECD）.The internal standards were used for quantitative determination.Result: A mixed standard solution prepared from primary standards of 9 organochlorine and 3 pyre-throid pesticide.The calibration curve for each of 12 organochlorine and pyrethroid pesticide was prepared covering the concentration ranges of 1 to 200 or 5 to 1 000 μg.L-1.The average recoveries and RSD were in the range of 82.0%-106.8% and 0.2%-7.9% at three organochlorine and pyrethroid pesticides levels respectively.The limits of detection were 0.15-13 μg.kg-1.There were no organochlorine and pyrethroid pesticide detected in 15 batches samples.Conclusion: This method was effective

fast and accurate.It has good repeatability and suitable for the analysis of organochlorine and pyrethroid pesticide in polygonum orientale.