SUN Jing1, LI Xiao-dong2, WANG Lu-jun2. Experimental Study on Yexiaotong for Sensitizing Effect of Radiotherapy in Treatment of Esophageal Cancer[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(1): 100-102.
SUN Jing1, LI Xiao-dong2, WANG Lu-jun2. Experimental Study on Yexiaotong for Sensitizing Effect of Radiotherapy in Treatment of Esophageal Cancer[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(1): 100-102. DOI: 10.13422/j.cnki.syfjx.2011.01.041.
Objective: To study the increased effect of Yexiaotong combined with radioactive rays on human esophageal cancer cells(TE-1) through experimental test.Method: The IC10 of Yexiaotong to TE-1 was obtained by MTT test.TE-1 cells were divided into two groups: one is treated by radiotherapy and the other by radiotherapy combined with Yexiaotong in 10% inhibition concentration IC10.Radiosensitivity was determined by clonogenic assay and quantified by calculating TER.Result: MTT assay showed that Yexiaotong had inhibitory effects on TE-1
and the 10% inhibition concentration was 61 g.L-1.Yexiaotong had a radio sensitizing effect
and the TER was 1.17.Conclusion: Yexiaotong can sensitize the effect of radiotherapy on TE-1
and the TER reaches 1.17
for which it is useful in radiotherapy in the future.