微乳闪式提取丹参脂溶性成分研究

任彦飞; 易红; 高进; 杨华

doi:10.13422/j.cnki.syfjx.2011.02.014

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微乳闪式提取丹参脂溶性成分研究

工艺与制剂 | 更新时间：2024-09-23

- 微乳闪式提取丹参脂溶性成分研究
- Study on Application of Smashing Tissue Extraction in Extracting Fat-Soluble Compounds of Salvia Miltiorrhiza by Microemulsion
- 中国实验方剂学杂志 2011年17卷第2期页码：15-17
- 作者机构：
  
  中国中医科学院中药研究所
- 作者简介：
- 基金信息：
  
  “重大新药创制”科技重大专项（2009ZX09301）、（2009ZX09308）;中国中医科学院自主选题项目（Z02094）
- DOI：10.13422/j.cnki.syfjx.2011.02.014
  中图分类号： R284.1
- 纸质出版日期：2011
- 稿件说明：
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[1]任彦飞,易红,高进,杨华.微乳闪式提取丹参脂溶性成分研究[J].中国实验方剂学杂志,2011,17(02):15-17+20.

REN Yan-fei, YI Hong, GAOJin, et al. Study on Application of Smashing Tissue Extraction in Extracting Fat-Soluble Compounds of Salvia Miltiorrhiza by Microemulsion[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 15-17.
[1]任彦飞,易红,高进,杨华.微乳闪式提取丹参脂溶性成分研究[J].中国实验方剂学杂志,2011,17(02):15-17+20. DOI： 10.13422/j.cnki.syfjx.2011.02.014.

REN Yan-fei, YI Hong, GAOJin, et al. Study on Application of Smashing Tissue Extraction in Extracting Fat-Soluble Compounds of Salvia Miltiorrhiza by Microemulsion[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 15-17. DOI： 10.13422/j.cnki.syfjx.2011.02.014.

摘要

目的:探讨微乳技术与闪式提取结合应用于丹参脂溶性成分提取的适用性。方法:以丹参酮ⅡA的提取率作为丹参脂溶性成分的指标

分别比较不同提取方式和不同溶剂对丹参中丹参酮ⅡA提取率的影响;采用正交设计

对丹参微乳闪式提取工艺的影响因素进行考察。结果:以微乳为溶剂

闪式提取可在数分钟内提取出丹参中80%～90%的丹参酮ⅡA;工艺条件中提取次数和微乳的稀释倍数对丹参酮ⅡA的提取率有非常显著影响。结论:微乳技术结合闪式提取应用于中药丹参有效成分的提取具有高效、快速的特点

应用前景良好。

Abstract

Objective:To study the feasibility of extracting salvia miltiorrhiza by smashing tissue extraction and microemulsion technology.Method:To measure the content of tanshinon ⅡA in salvia miltiorrhiza microemulsion extracting solution by HPLC.Making microemulsion as a solvent to extract salvia miltiorrhiza by smashing tissue extraction

heating countercurrent extraction

ultrasonic extraction and compare the extraction rate of tanshinonⅡA.U-sing orthogonal design to analyze on effect factors of the smashing tissue extraction.Result:The extraction rate of tanshinon ⅡA is 80%～90% by smashing tissue extraction and microemulsion technology.Extraction frequency and microemulsion dilution multiple of smashing tissue extraction have very significant impact on the extraction rate of tanshinon ⅡA.Conclusion:Combination smashing tissue extraction with microemulsion technology to extract the active compounds of salvia miltiorrhiza has efficient and fast characteristics and better application prospect.

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