黄连-厚朴配伍比例对和厚朴酚、厚朴酚溶出的影响

王术玲; 姚玉铿; 曾建波

doi:10.13422/j.cnki.syfjx.2011.02.015

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黄连-厚朴配伍比例对和厚朴酚、厚朴酚溶出的影响

工艺与制剂 | 更新时间：2024-09-23

- 黄连-厚朴配伍比例对和厚朴酚、厚朴酚溶出的影响
- Influence of Different Compatibilities between Coptidis Rhizoma and Magnoliae Officinalis Cortex on Dissolution of Honokiol and Magnolol
- 中国实验方剂学杂志 2011年17卷第2期页码：18-20
- 作者机构：
  
  广州中医药大学中药学院
- 作者简介：
- 基金信息：
  
  广州中医药大学本科生创新实验
- DOI：10.13422/j.cnki.syfjx.2011.02.015
  中图分类号： R284
- 纸质出版日期：2011
- 稿件说明：
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[1]王术玲,姚玉铿,曾建波.黄连-厚朴配伍比例对和厚朴酚、厚朴酚溶出的影响[J].中国实验方剂学杂志,2011,17(02):18-20.

WANG Shu-ling, YAO Yu-keng, ZENG Jian-bo. Influence of Different Compatibilities between Coptidis Rhizoma and Magnoliae Officinalis Cortex on Dissolution of Honokiol and Magnolol[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 18-20.
[1]王术玲,姚玉铿,曾建波.黄连-厚朴配伍比例对和厚朴酚、厚朴酚溶出的影响[J].中国实验方剂学杂志,2011,17(02):18-20. DOI： 10.13422/j.cnki.syfjx.2011.02.015.

WANG Shu-ling, YAO Yu-keng, ZENG Jian-bo. Influence of Different Compatibilities between Coptidis Rhizoma and Magnoliae Officinalis Cortex on Dissolution of Honokiol and Magnolol[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 18-20. DOI： 10.13422/j.cnki.syfjx.2011.02.015.

摘要

目的:探讨黄连-厚朴酸碱药对不同配伍比例对和厚朴酚、厚朴酚溶出的影响。方法:采用高效液相色谱法测定黄连-厚朴药对煎煮液中和厚朴酚及厚朴酚的含量。结果:和厚朴酚在黄连∶厚朴=1∶3时溶出最多

厚朴酚在黄连∶厚朴=1∶1时溶出最多

两者总量在黄连∶厚朴1∶1时最高

2∶1时最低。结论:黄连-厚朴不同配伍比例对和厚朴酚及厚朴酚的溶出有影响

可能与黄连中的生物碱有关。

Abstract

Objective:To study the influence of different compatibilities between Coptidis Rhizoma and Magnoliae Officinalis Cortex on dissolution of honokiol and magnolol.Method:High performance liquid chromatography was used to determine the content of honokiol and magnolol in all decoctions of Coptidis Rhizoma and Magnoliae Officinalis Cortex.Result:The maximum content of honokiol and magnolol was extrated when the ratio of Coptis to Magnolia was 1∶ 3 and 1∶ 1 respectively.The maximun total content of both components was extracted when the ratio was 1∶ 1 and the minimum when the ratio was 2∶ 1.Conclusion:Different compatibilities ratios between Coptidis Rhizoma and Magnolia Officinalis Cortex affected the dissolution of honokiol and magnolol

and it was probably related to the berberine alkaloids in Coptidis Rhizoma.

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