GUO Shan-shan, LIU Ying, GAO Ying-jie, et al. Effect of Xiaoer Feire Kechuan Oral Solution on Mice Infected by Influenza Virus A (H1N1)[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 152-155.
GUO Shan-shan, LIU Ying, GAO Ying-jie, et al. Effect of Xiaoer Feire Kechuan Oral Solution on Mice Infected by Influenza Virus A (H1N1)[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(2): 152-155. DOI: 10.13422/j.cnki.syfjx.2011.02.045.
Objective:To observe the effect of Xiaoer Feire Kechuan oral solution on the mice infected by influenza virus A(H1N1).Method:ICR mice were infected by influenza A(H1N1) with nasal drops(20
10
5 mL.kg-1)
the lung index
death rate
death protection rate and life prolongation were observed and the levels of cytokines in blood serum were detected by ELISA.Result:With treatment of Xiaoer Feire Kechuan oral solution
the lung index
death rate of ICR mice were decreased significantly
while the life span of mice was prolonged.There was no remarkable effect of Xiaoer Feire Kechuan oral solution on the cytokine levels in serum.Conclusion:Xiaoer Feire Kechuan oral solution could inhibit viral pneumonia for mice infected by influenza virus A(H1N1)significantly.