Objective:To evaluate the clinical efficacy and safety about interventional treatment for elderly patients with advanced primary liver cancer by Brucea javanica oil emulsion.Method: Fifty elderly patients with advanced primary liver cancer inpatients were randomly divided into treatment group（26 cases） and control group（24 cases）.Using Seldinger’s technique in both groups hepatic artery interventional therapy was carried out.Treatment group was treated with B.javanica oil /lipiodol mixture perfusion embolization;the control group received conventional chemotherapy /lipiodol chemoembolization infusion.Two groups

as the case in general interval 4 to 6 weeks to repeat one intervention.An average of 2.6 times for every routine intervention were observed in patients with clinical benefit rate

toxicity and survival.Result: The clinical benefit rates of the two groups after treatment were statistically significant difference（P < 0.05）.The incidence of toxic side effects in the treatment group was less than that in the control group after the intervention.No death case after treatment of 3 months in two groups.However

to compare the 0.5 and 1-year survival rate

treatment group were 96.1%（25/26）

50%（13/26）

the control group were 83.3%（20 /24）

33.3%（8/24）.There was significant difference between the treatment group and the control group（P<0.05）.Two group cases with a median survival time were 8.9 months and 6.7 months.Conclusion: Interventional treatment for advanced primary liver cancer by B.javanica oil emulsion is valid

low toxic side effects

especially suitable for elderly patients.